I got my results from my visit to Dr. KK and most of it seemed to be normal with a few exceptions. The phone consultation is over and here are my results.
Anti-phospholipid antibodies
IgG-Cardiolipin - Borderline
IgG-Phosphatidic Acid - Borderline
Treatment: Lovenox (Heparin) Shots 40mg/day starting CD 6. This will also increase the blood-flow to the Uterus and Ovaries. My blood flow was 2 out of 5 as measured during the u/s. Also need to do a followup U/S after 2 weeks on Lovenox to check blood blow and accordingly adjust Lovenox dosage. The resistance index was 0.6 last time. It needs be be less than 0.4.
NK (Natural Killer Cells) Assay
%CD 19 Result - 14.5 Range (2-12) - Slightly elevated
%CD 56 Result - 12.4 Range (2-12) - Slightly elevated
TH1:TH2 Intracellular Cytokine Ratios
TNF-a : IL-10 Result - 45.1 Range (13.2 - 30.6) - High
IFN-g : IL-10 Result - 35.0 Ratio (5.8 - 20.5) - High
Treatment : Dr KK recommends IVIG preconceptually and after conception. Since IVIG is expensive, there is high probability that insurance won't cover it. If so, I may chose to do steroids instead of IVIG.
Immunoglobulin Panel
IgG Result - 1680 Range (751-1560) - High
I need to do another blood test locally to recheck these levels. Any Idea why IgG would be high?
DHEA
Result - 1050 Range (102-1185 ng/dL)
I am not on DHEA supplements. Dr KK felt it was slightly high.
All the remaining tests were normal -some of which were Thyroid Panel, Metabolic Panel, CBC w/differential, MTHFR, Anti-DNA, Anti-Thyroid Antibodies, PAI-1 4G/5G Gene Polymorphism, Factor XIII, beta- Fibrinogen, HPA-1a, ANA, Testosterone, Vitamin D, Protein C, Protein S and so on.
I am glad that I have some answers and that my trip to Chicago was helpful. I at least know that I have autoimmune issues which need to be treated. I am hoping that I can get around without IVIG. I am ready to try steroids and lovenox. I am thinking that I should go with the Lap & Hysteroscopy on Oct 23rd before I start Dr KK's treatment. Hopefully, the Laparoscopy will help me know if there are problems conceiving and Dr.KK's treatment should help me to sustain a pregnancy if I conceive.
Anti-phospholipid antibodies
IgG-Cardiolipin - Borderline
IgG-Phosphatidic Acid - Borderline
Treatment: Lovenox (Heparin) Shots 40mg/day starting CD 6. This will also increase the blood-flow to the Uterus and Ovaries. My blood flow was 2 out of 5 as measured during the u/s. Also need to do a followup U/S after 2 weeks on Lovenox to check blood blow and accordingly adjust Lovenox dosage. The resistance index was 0.6 last time. It needs be be less than 0.4.
NK (Natural Killer Cells) Assay
%CD 19 Result - 14.5 Range (2-12) - Slightly elevated
%CD 56 Result - 12.4 Range (2-12) - Slightly elevated
TH1:TH2 Intracellular Cytokine Ratios
TNF-a : IL-10 Result - 45.1 Range (13.2 - 30.6) - High
IFN-g : IL-10 Result - 35.0 Ratio (5.8 - 20.5) - High
Treatment : Dr KK recommends IVIG preconceptually and after conception. Since IVIG is expensive, there is high probability that insurance won't cover it. If so, I may chose to do steroids instead of IVIG.
Immunoglobulin Panel
IgG Result - 1680 Range (751-1560) - High
I need to do another blood test locally to recheck these levels. Any Idea why IgG would be high?
DHEA
Result - 1050 Range (102-1185 ng/dL)
I am not on DHEA supplements. Dr KK felt it was slightly high.
All the remaining tests were normal -some of which were Thyroid Panel, Metabolic Panel, CBC w/differential, MTHFR, Anti-DNA, Anti-Thyroid Antibodies, PAI-1 4G/5G Gene Polymorphism, Factor XIII, beta- Fibrinogen, HPA-1a, ANA, Testosterone, Vitamin D, Protein C, Protein S and so on.
I am glad that I have some answers and that my trip to Chicago was helpful. I at least know that I have autoimmune issues which need to be treated. I am hoping that I can get around without IVIG. I am ready to try steroids and lovenox. I am thinking that I should go with the Lap & Hysteroscopy on Oct 23rd before I start Dr KK's treatment. Hopefully, the Laparoscopy will help me know if there are problems conceiving and Dr.KK's treatment should help me to sustain a pregnancy if I conceive.
I'm wondering if you have/had an infection which caused the igg levels to be elevated? Or maybe it's linked to the autoimmune issues. I'm glad you got some answers and have a plan. Blessings as you begin a new leg of your journey.
ReplyDeleteWow. I don't know what any of that means, but I'm glad you're getting answers!
ReplyDeleteI will pray for you! I just found your blog through another blog. God bless you!
ReplyDeleteMy goodness, even as a RN a lot of that sounds Greek to me. I am glad you got some answers..praying for you!!
ReplyDeleteSo glad you got some answers and if I were deciding I would have the lap before going forward with treatments - there's nothing like visually seeing everything to make sure all is clear and nothing is lurking that treatment may either make worse or would make treatment neutral.
ReplyDeletePrayers as you move forward - this is all so much to read, let alone digest and process.
Just to throw out there, I know Dr KK isn't a big advocate for Intralipid therapy, but it works similarly to IVIg. - much less expensive and my insurance at the time actually covered the med and the administration of it.
ReplyDeleteLooking back, not sure I needed either. But all the research I did I do think IVIg is a superior treatment option if at all possible. However, a cheaper alternative does exist. Sher Institutes use Intralipids.
I am so glad you have some answers and a good treatment plan. Will be praying!
Okay I didn't understand most of that but I'm praying for good results for you!!
ReplyDeleteWow...what a ton of results and information you got. Praying all that info leads you to a treatment plan that allows you to carry a pregnancy full-term!
ReplyDelete